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Search Result

Search Results for " factor xa "

20

Compounds

Cat No. Product Name Synonyms Targets
T10174 5-R-Rivaroxaban Factor Xa
5-R-Rivaroxaban is (R)-enantiomer of Rivaroxaban. Rivaroxaban (BAY 59-7939) is a highly potent and selective, direct Factor Xa (FXa) inhibitor (IC50 0.7 nM; Ki 0.4 nM).
T4980 Betrixaban maleate Factor Xa
Betrixaban maleate is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa.
T0372 Gabexate mesylate FOY Factor Xa , Serine Protease , Proteasome
Gabexate mesylate (FOY) is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inh...
T1736 Apixaban BMS-562247-01 Factor Xa
Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and pr...
T1184 Rivaroxaban BAY 59-7939 Factor Xa , Thrombin
Rivaroxaban (BAY 59-7939) is an orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon oral administration, rivaroxaban selectively binds to both ...
T4341 Betrixaban PRT054021 Factor Xa
Betrixaban (PRT054021) is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among all lead compounds due to its low hERG channel ...
T22323 Enoxaparin sodium Thrombin
Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment myocardial infarction (STEMI), or STEMI with subsequent percu...
T8362 Benzamidine hydrochloride Benzamidine HCl Serine/threonin kinase , Serine Protease
Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively).
T31206 Darexaban YM 150,Darexaban, Tanexaban,YM150 Factor Xa
Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothrombin activity at the site of blood clot (thrombus) formati...
T4076 Fondaparinux sodium Natural heparin pentasaccharide Sodium,Fondaparin sodium,SR-90107A,Arixtra Factor Xa
Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.
T2368 Edoxaban Tosylate Monohydrate DU-176b,DU-176b tosylate Monohydrate,Lixiana,Edoxaban Factor Xa , Thrombin
Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.
T67853 Rivaroxaban Impurity Rivaroxaban-10 Factor Xa
Rivaroxaban Impurity (Rivaroxaban-10) is a potent Blood-coagulation factor Xa inhibitor, IC50= 66 nM.
T27257 EMD-503982 EMD 503982
EMD-503982 is a factor Xa inhibitor.
T20454 4-Chlorophenylurea NSC12971,NSC 12971,NSC-12971 Factor Xa
4-Chlorophenylurea (NSC-12971) is a novel orally bioavailable inhibitor of factor Xa.
T31668 Eribaxaban PD 348292,PD0348292,PD-0348292,PD-348292,PD 0348292,PD348292 Factor Xa
Eribaxaban (PD348292) is an orally available factor Xa inhibitor for the prevention and treatment of venous thromboembolism.
T4690 Betrixaban hydrochloride(330942-05-7(free base)) PRT054021 hydrochloride Factor Xa
Betrixaban hydrochloride(330942-05-7(free base)) (PRT054021 hydrochloride) is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5 nM).
T27920 LY 517717 LY-517717,LY517717 Factor Xa
LY 517717 is an orally active inhibitor of coagulation factor Xa with antithrombotic activity for the study of venous thromboembolism (VTE).
T27318 Fidexaban CI-1031,BX-807834,PD-200022,CI1031,BX807834,ZK-807834 Factor Xa
Fidexaban (CI1031) is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assays
T29215 Zifaxaban TY 602,TY602,TY-602 Factor Xa
Zifaxaban (TY-602) is an orally active, competitive and selective inhibitor of factor Xa (FXa) with an IC50 of 11.1 nM for human FXa.Zifaxaban has a very high affinity, more than 10,000-fold higher than that of other ser...
T66256 Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate Factor Xa
Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate has an inhibitory effect on coagulation factor Xa, and it can be used in the study of thrombop...

Compounds

5-R-Rivaroxaban
T10174
Synonym:
Target: Factor Xa
Betrixaban maleate
T4980
Synonym:
Target: Factor Xa
Gabexate mesylate
T0372
Synonym: FOY
Target: Factor Xa, Serine Protease, Proteasome
Apixaban
T1736
Synonym: BMS-562247-01
Target: Factor Xa
Rivaroxaban
T1184
Synonym: BAY 59-7939
Target: Factor Xa, Thrombin
Betrixaban
T4341
Synonym: PRT054021
Target: Factor Xa
Enoxaparin sodium
T22323
Synonym:
Target: Thrombin
Benzamidine hydrochloride
T8362
Synonym: Benzamidine HCl
Target: Serine/threonin kinase, Serine Protease
Darexaban
T31206
Synonym: YM 150,Darexaban, Tanexaban,YM150
Target: Factor Xa
Fondaparinux sodium
T4076
Synonym: Natural heparin pentasaccharide Sodium,Fondaparin sodium,SR-90107A,Arixtra
Target: Factor Xa
Edoxaban Tosylate Monohydrate
T2368
Synonym: DU-176b,DU-176b tosylate Monohydrate,Lixiana,Edoxaban
Target: Factor Xa, Thrombin
Rivaroxaban Impurity
T67853
Synonym: Rivaroxaban-10
Target: Factor Xa
EMD-503982
T27257
Synonym: EMD 503982
Target:
4-Chlorophenylurea
T20454
Synonym: NSC12971,NSC 12971,NSC-12971
Target: Factor Xa
Eribaxaban
T31668
Synonym: PD 348292,PD0348292,PD-0348292,PD-348292,PD 0348292,PD348292
Target: Factor Xa
Betrixaban hydrochloride(330942-05-7(free base))
T4690
Synonym: PRT054021 hydrochloride
Target: Factor Xa
LY 517717
T27920
Synonym: LY-517717,LY517717
Target: Factor Xa
Fidexaban
T27318
Synonym: CI-1031,BX-807834,PD-200022,CI1031,BX807834,ZK-807834
Target: Factor Xa
Zifaxaban
T29215
Synonym: TY 602,TY602,TY-602
Target: Factor Xa
Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
T66256
Synonym:
Target: Factor Xa
1 2 3 4
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